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VOLUME 19 , ISSUE 1 ( January, 2018 ) > List of Articles


Comparative Evaluation of Remineralizing Effect of Novamin and Tricalcium Phosphate on Artificial Caries: An in vitro Study

Guneet Guram, Umang Jagga, Uttam Paul, Arpita Kashyap, Vivek Padmanabhan, Kiran Keswani

Citation Information : Guram G, Jagga U, Paul U, Kashyap A, Padmanabhan V, Keswani K. Comparative Evaluation of Remineralizing Effect of Novamin and Tricalcium Phosphate on Artificial Caries: An in vitro Study. J Contemp Dent Pract 2018; 19 (1):109-112.

DOI: 10.5005/jp-journals-10024-2221

License: CC BY-NC 3.0

Published Online: 01-01-2018


Aim: The aim of the present study was to compare the remineralizing efficacy of novamin and tricalcium phosphate (TCP). Materials and methods: Nail varnish was coated to a total of 30 sound human premolars except for 5 mm × 5 mm window. Baseline microhardness was measured for all test samples. Artificial carious lesions were created for all teeth by subjecting them to demineralization process. Then microhardness of demineralized lesion was measured. Later artificial caries teeth were equally divided into two groups to treat with remineralization solution for 10 days; group I: novamin and group II: TCP. After 10 days of pH cycling, microhardness was measured. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) statistical software from Chicago SPSS Inc., version 21 and using analysis of variance (ANOVA) post hoc multiple comparisons test for intergroup and significant difference at p < 0.05. Results: In the present study, group I indicated a higher value for remineralization compared with group II (p < 0.05). Conclusion: The present study showed that both novamin and TCP were effective in remineralizing the carious lesions. Clinical significance: This study evaluates the remineralizing potential of novamin and TCP on initial carious lesions.

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  1. Mehta AB, Kumari V, Jose R, Izadikhah V. Remineralization potential of bioactive glass and casein phosphopeptideamorphous calcium phosphate on initial carious lesion: an in-vitro pH-cycling study. J Conserv Dent 2014 Jan;17(1):3-7
  2. Comparative evaluation of remineralizing potential of three agents on artificially demineralized human enamel: an in vitro study. J Conserv Dent 2013 Mar;16(2):116-120
  3. A comparative evaluation of remineralizing ability of bioactive glass and amorphous calcium phosphate casein phosphopeptide on early enamel lesion. Dent Res J (Isfahan) 2016 Jul-Aug;13(4):297-302
  4. Remineralization effect of topical novamin versus sodium fluoride (1.1%) on caries-like lesions in permanent teeth. J Dent (Tehran) 2012 Winter;9(1):68-75
  5. Remineralizing effect of topical novamin and nano-hydroxyapatite on carieslike lesions in primary teeth. J Contemp Dent Pract 2016 Aug;17(8):645-649
  6. Effect of proanthocynidin, fluoride and casein phosphopeptide amorphous calcium phosphate remineralizing agents on microhardness of demineralized dentin. J Dent (Tehran) 2017 Mar;14(2):76-83
  7. Reminearalization potential of fluoride and amorphous calcium phosphate-casein phosphate peptide on enamel lesion: an in vitro evaluation. J Conserv Dent 2010 Jan;13(1):42-46
  8. Effect of three different remineralizing agents on enamel caries formation— an in vitro study. Kathmandu Univ Med J (KUMJ) 2014 Jan-Mar;12(45):16-20
  9. Remineralization effects of a two-solution fluoride mouthrinse: an in situ study. J Dent Res 2000 Apr;79(4):991-995
  10. An in vitro evaluation of remineralization potential of novamin on artificial enamel sub-surface lesions around orthodontic brackets using energy dispersive x-ray analysis (EDX). J Clin Diagn Res 2014 Nov;8(11):ZC88-ZC91
  11. Evaluation to determine the caries remineralization potential of three dentifrices: an in vitro study. J Conserv Dent 2013 Jul-Aug;16(4):375-379
  12. Effect of green and white tea pretreatment on remineralization of demineralized dentin by cpp-acfp-an in vitro microhardness analysis. J Clin Diagn Res 2016 Apr;10(4):ZC85-ZC89
  13. Comparative evaluation of two different remineralizing agents on the microhardness of bleached enamel surface: results of an in vitro study. Indian J Dent Res 2015 Mar-Apr;26(2):176-179
  14. Remineralizing effect of different topical agents on occlusal surfaces with or without caries: an in vitro evaluation study using electrical resistance measurement. Clin Dent Res 2012 Aug;36(3):4-9
  15. An in vitro study to evaluate and compare the effects of various commercially available remineralizing agents on surface microhardness of artificially produced enamel lesions. Int J Clin Prev Dent 2017 Jun;13(2):67-72.
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