The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 5 , ISSUE 3 ( August, 2004 ) > List of Articles

RESEARCH ARTICLE

Neoplasms of the Salivary Glands: A Descriptive Retrospective Study of 142 Cases-Mulago Hospital Uganda

Arabat Kasangaki, Adrian Kamulegeya

Citation Information : Kasangaki A, Kamulegeya A. Neoplasms of the Salivary Glands: A Descriptive Retrospective Study of 142 Cases-Mulago Hospital Uganda. J Contemp Dent Pract 2004; 5 (3):16-27.

DOI: 10.5005/jcdp-5-3-16

License: CC BY-NC 3.0

Published Online: 01-05-2006

Copyright Statement:  Copyright © 2004; The Author(s).


Abstract

Objective

This study was aimed at establishing the prevalence, sex, age, and site distribution of salivary gland neoplasms as seen in the Department of Oral Surgery Mulago Hospital Uganda.

Design

Descriptive retrospective study.

Materials and Methods

Histopathological results from the Department of Oral Surgery were retrieved and analyzed for histological diagnosis, age, sex, and site. Records retrieved included those from January 1988 to December 2000. Student's t-test and z-test were used for data analysis.

Results

Of all neoplasms seen in the Department between 1988 and 2000, salivary gland tumors comprised 7.8% of which 77 (54.23%) were benign and 65 (45.77%) were malignant. Pleomorphic adenoma was the most prevalent over all. Among the malignant group, adenocarcinoma was the most prevalent of those where the palate was the most affected site. The age range was 1-80 years with the overall mean age being 33.83 ± 18. 83. The mean age for the benign lesions was 26.74 ± 16.0 and for the malignant lesions was 42.49 ± 19.15.

Conclusion

The findings were in agreement with most African studies but differed from studies from the other continents. Pleomorphic adenoma was the most prevalent salivary gland neoplasm with both males and females affected equally. More research is needed on specific salivary gland neoplasms in Uganda and preferentially on a regional basis geographically. However, if valid data on the diagnosis as well as age, site, and sex distribution are to be obtained, an improvement in the standardization of diagnosis and reporting of patient data will be necessary.

Citation

Kasangaki A, Kamulegeya A. Neoplasms of the Salivary Glands: A Descriptive Retrospective Study of 142 Cases-Mulago Hospital Uganda. J Contemp Dent Pract 2004 August;(5)3:016-027.


PDF Share
  1. Essentials of dental surgery and pathology 4th edition. Churchill Livingstone Medical Division of Longman Group UK Ltd. 1984. 298-311. ISBN 044304015X.
  2. Salivary gland tumours in Ibadan, Nigeria: a study of 295 cases. Afr J Med Med Sci. 1990 Sep;19(3):195-9.
  3. Oral tumours and tumour-like conditions in Kenya: I. Histological distribution. East Afr Med J. 1995 Sep;72(9):560-3.
  4. J. Tumors of the jaws. East African Medical Journal Oct. 1995 33(10):383-390
  5. Tumors of minor salivary glands and the analysis of 106 cases. J Okla Dent Assoc. 1996 Spring;86(4):50-2. Review.
  6. al. Salivary gland lesions: a Jamaican perspective. West Indian Med J. 2001 Mar;50(1):62-5.
  7. al. Minor salivary gland tumours. A retrospective study of 164 cases in a Brazilian population. Eur J Cancer B Oral Oncol. 1995 May;31B(3):197-201.
  8. Salivary gland tumors in Jordan: A retrospective study of 221 patients. The Croatian Medical Journal March 1999 Volume 40 Number 4 (Medline).
  9. al. Descriptive epidemiology of oral neoplasms in Sudan 1970- 1985 and the role of toombak. Int J Cancer. 1995 Apr 10;61(2):155-8.
  10. Intraoral salivary gland neoplasms: a retrospective study of seventy cases in an African population. Oral Surg Oral Med Oral Pathol. 1991 May;71(5):579-82.
  11. al. Intraoral minor salivary gland tumors: a retrospective study of 129 cases. J Nihon Univ Sch Dent. 1997 Sep;39(3):128-32.
  12. Tumours of the minor (oropharyngeal) salivary glands: a demographic study of 336 cases. J Oral Pathol. 1985 Jul;14(6):500-9.
  13. Clinicopathologic study of 206 cases in Zimbabwe. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jun;79(6):747-9.
  14. Salivary gland neoplasms in Lagos, Nigeria. West Afr J Med. 1996 Jan-Mar;15(1):11-7.
  15. V. and Southam. J.C. Oral Pathology 2nd edition Oxford Medical Publications 1993, 245-253. ISBN 0192622153
  16. al. Salivary gland tumors in a Brazilian population: a retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo. 2002 Nov-Dec;57(6):271-6. Epub 2003 Feb 17.
  17. Salivary gland tumors in the parotid gland, submandibular gland, and the palate region. Cancer. 1971 Jun;27(6):1415-8. No abstract available.
  18. Intraoral minor salivary gland tumors. An analysis of 1,414 cases. Oral Surg Oral Med Oral Pathol. 1961 Oct;14:1194-226. No abstract available.
  19. Salivary gland tumours in Zimbabwe: report of 282 cases. Int J Oral Maxillofac Surg. 1995 Aug;24(4):293-7.
  20. al. WHO International Histological Classification of Tumours. Tentative Histological Classification of Salivary Gland Tumours. Pathol Res Pract. 1990 Oct;186(5):555-81.
  21. al. Salivary gland tumours in Kenya. East Afr Med J. 1992 Sep;69(9):525-30. 69(9) 525-530.
  22. Carcinoma ex pleomorphic adenoma: pathologic analysis of 73 cases. Hum Pathol. 2001 Jun;32(6):596-604.
  23. Salivary gland neoplasms: a descriptive analysis of the pattern seen in Enugu. West Afr J Med. 1999 Jul-Sep;18(3):179-82.
  24. Salivary gland tumors of the lip. Arch Otolaryngol. 1982 Jan;108(1):45-7.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.