The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 6 , ISSUE 4 ( November, 2005 ) > List of Articles

RESEARCH ARTICLE

Squamous Cell Carcinoma of the Oral Tissues: A Comprehensive Review for Oral Healthcare Providers

Samer A. Bsoul, Geza T. Terezhalmy, Michaell A. Huber

Citation Information : Bsoul SA, Terezhalmy GT, Huber MA. Squamous Cell Carcinoma of the Oral Tissues: A Comprehensive Review for Oral Healthcare Providers. J Contemp Dent Pract 2005; 6 (4):1-16.

DOI: 10.5005/jcdp-6-4-1

License: CC BY-NC 3.0

Published Online: 01-11-2005

Copyright Statement:  Copyright © 2005; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Citation

Bsoul SA, Huber MA, Terezhalmy GT. Squamous Cell Carcinoma of the Oral Tissues: A Comprehensive Review for Oral Healthcare Providers J Contemp Dent Pract 2005 November;(6)4:001-016.


PDF Share
  1. Cancer genetics. Nature. 2001;411:336-341.
  2. Genome maintenance for preventing cancer. Nature. 2001;100:57-70.
  3. Anticancer drug targets: cell cycle and checkpoint control. 1999;104(12):1645-1653.
  4. Effects of the consumption of alcohol in the oral cavity: Relationship with oral cancer. Med Oral 2004;9:14-23.
  5. Epidemiology and prevention of oral cancer. Oral Oncol 1997;33:302-12.
  6. Indentification of risk groups for oral precancer and cancer and preventive measures. Clin Oral Invest 2001;5:207-13.
  7. Tobacco usage in relation to the anatomical site of oral leukoplakia. Oral Dis 2001;7:25-7.
  8. Cigarette smoking among adults – United States, 2002. MMWR 2004;53:427-431.
  9. Tobacco and cancer: Recent epidemiological evidence. J Natl Cancer Inst 2004;96:99-106.
  10. Human papilloma virus type 16 E6 gene expression in oral exophytic epithelial lesions as detected by in situ rtPCR. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87:197-208.
  11. Detection of HPV-16 genome in human oral cancers and potentially malignant lesions from India. Oral Oncol 1998;34:413-20.
  12. Molecular piracy: the viral ink to carcinogenesis. Oral Oncol 1998;34:448-53.
  13. Human papilloma viruses in oral lesions. Anticancer Res 2000;20:1183-8.
  14. Oral squamous cell carcinoma; from an hypothesis about a virus, to concern about possible sexual transmission. Oral Oncol 2002;38:227-34.
  15. Human papillomavirus in oral exfoliated cells and risk of head and neck cancer. J Natl Cancer Inst 2004;96:449-55.
  16. Oral cancer and mouthwash use: evaluation of the epidemiologic evidence. Otolaryngol Head Neck Surg. 1995 Sep;113(3):253-61.
  17. Adverse effects of mouthwash use. A review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;80:432-9.
  18. Maté: a risk factor for oral and oropharyngeal cancer. Oral Oncol 2002;38:646-9.
  19. Socioeconomic status, lifestyle factors and oral premalignant lesions. Oral Oncol 2003;39:664-71.
  20. Epidemiology and prevention of oral cancer. Oral Oncol 1997;33:302-12.
  21. Folate intake and risk of oral and pharyngeal cancer. Ann Oral Oncol 2003;14:1677-81.
  22. Squamous cells carcinoma of the head and neck in solid organ transplant recipients. Head Neck 2002;24:319-25.
  23. The causation of oral precancer and cancer. J Dent Assoc S Afr. 1989 Mar;Suppl 1:6-10.
  24. Chronic mechanical trauma in the aetiology of oropharyngeal carcinoma. J Maxillofac Surg. 1978 Aug;6(3):217-21.
  25. Relationship between dental factors and risk of upper aerodigestive tract cancer. Oral Oncol. 1998 Jul;34(4):284-91.
  26. Oral cancer in the UK: to screen or not screen. Oral Oncol 1998;34:454-65.
  27. Cancer statistics, 2004. CA Cancer J Clin 2004;54:8-29.
  28. Preventing and controlling oral and pharyngeal cancer. Recommendations from a national strategic planning conference. MMWR 1998;47 (No. RR-14).
  29. Trends in oral cancer rates in the United States, 1973-1996. Community Dent Oral Epidemiol 2000;28:249-56.
  30. Cancer facts and figures 2002. Atlanta, GA: American Cancer Society; 2002.
  31. Cancer of the oral cavity. Current Problems in Surgery 2000;37:634-731.
  32. Squamous cell carcinoma of the gingiva. A case series analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Aug;80(2):183-7.
  33. Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics. Crit Rev Oral Biol Med 2003;14:47-62.
  34. Diagnosis of early oral and oropharyngeal squamous carcinoma: obstacles and their amelioration. Oral Oncol 2000;36:253-55.
  35. Oral cancer and precancerous lesions. CA Cancer J Clin 2002;52:195-215.
  36. Progress in determining the malignant potential of oral lesions. J Oral Pathol Med 2003;32:251-6.
  37. Oral leukoplakia. A retrospective study of clinical and histological data. Schweiz Monatsschr Zahnmed. 2004;114(7):680-6.
  38. Pooled estimate of world leukoplakia prevalence: a systemic review. Oral Oncol 2003;39:770-80.
  39. Low prevalence of oral leukoplakia in a representative sample of the US population. Oral Oncol. 2003 Sep;39(6):619-25.
  40. Oral leukoplakia. Crit Rev Oral Biol Med 1995;6:147-160.
  41. Oral leukoplakia and erythroplakia: a review and update. Pract Periodontics Aesthet Dent. 1994 Aug;6(6):9-17.
  42. Health effects associated with smokeless tobacco: a systematic review. Thorax 2003;58:435-43.
  43. Proliferative verrucous leukoplakia: unusual locations of oral squamous cell carcinomas, and field cancerization as shown by the appearance of multiple OSCCs. Oral Oncol. 2004 Apr;40(4):440-3.
  44. Proliferative verrucous leukoplakia: a follow-up study of 54 cases. Oral. Surg Oral Med Oral Pathol Oral Radiol Endod 1997;84:154-157.
  45. Proliferative verrucous leukoplakia: high incidence of gingival squamous cell carcinoma. J Oral Pathol Med 2003;32:379-382.
  46. Proliferative verrucous leukoplakia a report of ten cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:396-401.
  47. Oral cancer development in patients with oral lichen planus. J Oral Pathol Med 1993;22:421-4.
  48. Oral lichen planus and its association with squamous cell carcinoma: an update on pathogenesis and treatment implications. Laryngoscope 1996;106:357-62.
  49. Clinical characteristics and treatment of patients with oral lichen planus in Israel. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82:644-9.
  50. Malignant development of lichen planus-affected oral mucosa. J Oral Pathol 1988;17:219-25.
  51. Clinical behaviour of malignant transforming oral lichen planus. Eur J Oral Surgical Oncol 2002;28:838-43.
  52. Update on oral lichen planus: Etiopathogenesis and management. Crit Rev Oral Biol 1998;9:86-122.
  53. Oral lichen planus: A potentially premalignant lesion. J Oral Maxillofac Surg 2000;58:1286-8.
  54. The bullous desquamtive lesions of oral mucosa. J Calif Dent Assoc 2000;28:928-32.
  55. The possible premalignant character of oral lichen planus and oral lichenoid lesions: A prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;96:164-71.
  56. The clinical features, malignant potential, and systemic associations of oral lichen planus: A study of 723 patients. J Am Acad Dermatol 2002;46:207-14.
  57. A retrospective study of oral lichen planus patients with concurrent or subsequent development of malignancy. Oral Oncol 1999;35:278-82.
  58. Erosive form of lichen planus. Otolaryngol Head Neck Surg 1999;121:844.
  59. Update on precancerous lesions. Dent Update 1999;26:382-6.
  60. Malignant transformation of oral lichen planus. Eur J Surg Oncol 1999;25:520-3.
  61. The possible association between oral lichen planus and oral squamous cell carcinoma: a clinical evaluation on 14 cases and a review of the literature. Oral Oncol 1998;34:239-46.
  62. Lichen planus: Exploring its malignant potential. J Am Dent Assoc 1993;124:102-8.
  63. Lichenoid lesions of the oral mucosa. Diagnostic criteria and their importance in the alleged relationship to oral cancer. Oral Surg Oral Med Oral Pathol 1992;73:699-704.
  64. Lichen planus and oral cancer: Is there a connection between the two? J Am Dent Assoc 1992;123:104-8.
  65. Oral lichen planus: A benign lesion. J Oral Maxillofac Surg 2000;58:1278-85.
  66. Oral lichen planus: the eveidence regarding potential malilgnant transformation. J Oral Pathol 1978;7:1-7.
  67. Oral lichen planus: Progress in understanding its malignant potential and the implications for clinical management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;96:32-7.
  68. Lichen planus and malignancy. An epidemiologic study of 2071 patients and review of the literature. Arch Dermatol 1991;127:1684-8.
  69. Lichen planus. Curr Opin Dent 1991;1:769-72.
  70. Polymorphism of the MICA gene and risk for oral submucous fibrosis. J Oral PAthol Med 2004;33:1-6.
  71. Oral submucous fibrosis: a case-control study in Chennai, South India. J Oral Pathol Med 2004;33:274-7.
  72. Oral submucous fibrosis in a a12-year old Bangladeshi boy: a case report and review of literature. Int J Pedatr Dent 2002;12:271-6.
  73. Synergistic effects of nicotine on arecoline-induced cytotoxicity in human buccal fibroblasts. J Oral Pathol Med 2001;30:458-64.
  74. Role of areca nut in betal quid-assocaited chemical carcinogensis: current awareness and future perspectives. Oral Oncol 2001;37:477-92.
  75. Total reconstruction for cancers associated with advanced oral submucous fibrosis. Ann Plast Surg 2003;51:283-9.
  76. The actinic (solar) keratosis. A 21st century perspective. Archives Dermatol 2003;139:66-70.
  77. Actinic cheilitis, report of a case. Oral Surg 1980;50:21-24.
  78. The lip-protect or neglect? Milit Med 1976;141:713-5.
  79. The prevalence of environmentally induced lip pathology among active duty soldiers. Milit Med 1981;146:186-8.
  80. The world cancer report and the burden of oral cancer. Eur J Cancer Prev 2004;13:139-42.
  81. Tobacco use as contributory factor in peptic ulcer disease. J Coll Physicians Surg Pak. 2003 Jul;13(7):385-7.
  82. Smokeless tobacco use, birth weight, and gestational age: population based, prospective cohort study of 1217 women in Mumbai, India. BMJ. 2004 Jun 26;328(7455):1538. Epub 2004 Jun 15.
  83. A smoking related triad: PAD, COPD and CCF. Aust Fam Physician. 2004 Apr;33(4):207-10.
  84. Smoking and cancer risk in Korean men and women. Cancer Causes Control. 2004 May;15(4):341-8.
  85. Paternal smoking and pregnancy loss: a prospective study using a biomarker of pregnancy. Am J Epidemiol. 2004 May 15;159(10):993-1001.
  86. Oral precancerous and malignant lesions associated with graft-versus-host disease: Report of 2 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:75-80.
  87. Skin cancers after transplantation. Nephrol Dial Transplant 2003;18:1052-8.
  88. Skin cancers after organ transplantation. N Engl J Med 2003;348:168-91.
  89. Incidence of skin cancer in 5356 patients following organ transplantation. Br J Dermatol 2000;143:513-9.
  90. Is oral cancer susceptibility inherited? Report of five oral cancer families. Eur J Cancer B Oral Oncol. 1996 Jan;32B(1):63-7.
  91. Family cancer history and susceptibility to oral carcinoma in Puerto Rico. Cancer. 2001 Oct 15;92(8):2102-8.
  92. Oral cancer examination. The best way to screen for oral cancer. J Dent Que 2004;Supplement:12-15
  93. The standard of care for oral diagnosis as it relates to oral cancer. Compend Contin Educ Dent 199819569-72. 574, 576 passim; quiz 584.
  94. An interim determination of health gain from oral cancer and precancer screening: 3. preselecting high risk individuals. Community Dent Health 1998;15:72-6.
  95. Screening for oral cancer of the head and neck; if not now, when? Oral Oncol 1997;33:313-6.
  96. Screening programmes for the early detection of oral cancer. Cochrane Database Syst Rev 2003;4:CD004150.
  97. Toluidine blue╌viewpoints. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87(5):526-7; author reply 528-9.
  98. The utility of toluidine blue application as a diagnostic aid in patients previously treated for upper oropharyngeal carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83(5):537-47.
  99. Early diagnosis of asymptomatic oral and oropharyngeal squamous cancers. CA Cancer J Clin 1995;45-328-51.
  100. Reliability of toluidine blue application in the detection of oral epithelial dysplasia and in situ and invasive squamous cell carcinomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91(5):535-40.
  101. Toluidine blue staining in the detection of oral precancerous and malignant lesions. Oral Surg Oral Med Oral Pathol 1984;57(4):379-82.
  102. Prevention, early detection and diagnosis of oral cancer. Dermatol Clin. 1987 Oct;5(4):675-80.
  103. Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer. Lasers Surg Med 1999;25:323-34.
  104. Diagnosis of oral cancer by light-induced autofluorescence spectroscopy using double excitation wavelengths. Oral Oncol 1999;35:144-50.
  105. Fluoresecence spectroscopy: a technique with potential to improve the early detection of aerodigestive tract neoplasia. Head Neck 1998;20:556-62.
  106. Characterization of autofluroescence in oral squamous cell carcinoma. Oral Oncol 2003;39:150-6.
  107. A comparative study of normal inspection, autofluourescence and 5-ALA-induced PPIX fluorescence for oral cnacer diagnosis. Int J Cancer 2002;97:245-52.
  108. Detection and diagnosis of oral cancer by light-induced fluorescence. Lasers Surg Med 2003;32(1):17-24.
  109. Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. Am J Surg 1996;172(6):674-7.
  110. Analysis of fluorescence in oral squamous cell carcinoma. Oral Oncol 2002;38(4):343-8.
  111. Spectroscopic detection and evaluation of morphologic and biochemical changes in early human oral carcinoma. Cancer 2003;97(7):1681-92.
  112. Roodenburg JL. Autofluorescence characteristics of healthy oral mucosa at different anatomical sites. Lasers Surg Med 2003;32(5):367-76.
  113. Computer-assisted analysis of oral brush biopsies at an oral cancer screening program. J Am Dent Assoc 2002 Mar;133(3):357-62.
  114. Improving detection of precancerous and cancerous oral lesions. Computer-assisted analysis of the oral brush biopsy. U.S. Collaborative OralCDx Study Group. J Am Dent Assoc 1999;130(10):1445-57.
  115. Oral brush biopsy: the problem of false positives. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;96:252.
  116. Oral brush biopsy: false positives redux. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;97:419.
  117. Oral malignancies associated with negative transepithelial brush biopsy. J Oral Maxillofac Surg. 2003;61:674-7.
  118. The oral brush biopsy: separating fact from fiction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;96:654-5.
  119. Comparison of computer-assisted brush biopsy results with follow up scalpel biopsy and histology. Gen Dent. 2002;50:500-3.
  120. Naked-eye inspection of the cervix after acetic acid application may improve the predictive value of negative cytologic screening. J Fam Prac 1994;39:457-460.
  121. Comparison of chemiluminescent light versus incandescent light in the visualization of acetowhite epithelium. Am J Gynecol Health 1992;6:11-15.
  122. Papanicolaou smear screening augmented by a magnified chemiluminescent exam. Int J Gynecol Obstet 1993;43:289-296.
  123. Comparison of magnified chemiluminescent examination with incandescent light examination and colposcopy for detection of cervical neoplasia. Ind J of Ca 1998;35:81-87.
  124. Effectiveness of the Papanicolaou smear and speculoscopy as compared with the Papanicolaou smear alone: A community-based clinical trial. Obstet Gynecol 1997;90(3):421-427.
  125. Acetic acid wash and chemiluminescent illumination as an adjunct to conventional oral soft tissue examination for the detection of dysplasia: a pilot study. Quintessence Int 2004;35(5):378-84.
  126. Correlation of imaging and clinical features in the assessment of mandibular invasion of oral carcinomas. Int J Oral Maxillofac Surg 1996;25(6):439-45.
  127. CT and MR imaging in tumors of the tongue, tongue base, and floor of the mouth: a comparative study. J Belge Radiol 1994 Apr;77(2):78-83.
  128. CT and MR imaging of squamous cell carcinoma of the tongue and floor of the mouth. Radiographics 1996;16(4):787-810.
  129. Diagnostic value of magnetic resonance imaging for malignant tumors in the oral and maxillofacial region. Diagnostic value of magnetic resonance imaging for malignant tumors in the oral and maxillofacial region. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996;82(6):691-7.
  130. Computed tomography of carcinoma of the upper gingiva and hard palate: correlation with the surgical and histopathological findings. Dentomaxillofac Radiol 1997;26(3):177-82.
  131. Assessment of tumour invasion into the mandible: the value of different imaging techniques. Eur Radiol 1998;8(9):1552-7.
  132. Predictors of carcinomatous invasion of the mandible. Head Neck 1994;16(2):116-26.
  133. Mandibular invasion by squamous cell carcinoma: a computed tomographic and histological study. Br J Oral Maxillofac Surg 1996;34(1):69-74.
  134. A comparison of segmental and marginal bony resection for oral squamous cell carcinoma involving the mandible. J Oral Maxillofac Surg 1997;55(5):470-7; discussion 477-8.
  135. Head and neck sites. In AJCC Cancer Staging Manual, ed 6. New York: Springer-Verlag, 2002:17-88.
  136. Recent advances in radiotherapy for head and neck cancers. Ear Nose Throat J 2001;80:704-17.
  137. Postoperative irradiation with or without concommintant chemotherapy for locally advanced head and neck cancer. N Engl J Med 2004;350:1945-52.
  138. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-44.
  139. Management of cancer of the head and neck – a cocktail with your PORT? N Engl J Med 2004;350:1997-9.
  140. Toxicity in head and neck cancer: a review of trends and issues. Int J Radiat Oncol Biol Phys 2000;47(1):1-12.
  141. Concurrent chemoradiotherapy in head and neck cancer. Curr Oncol Rep 1999;1(2)105-9. Review.
  142. Morbidity after midline mandibulotomy and radiation therapy. Am J Otolaryngol 2000;21:312-7.
  143. Cancer of retromolar trigone: Long-term radiation therapy outcome. Head Neck 2001;23:758-63.
  144. Clinical function after primary surgery for oral and oropharyngeal cancer: An 11-item examination. Br J Oral Maxillofac Surgeons 2002;40:1-10.
  145. Accelerated hyperfractionation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation. Br J Cancer 2002;86:517-23.
  146. Late morbidity: The Damocles sword of radiotherapy? Radiother Oncol 2001;61:219-221.
  147. Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers. Radiother Oncol 2000;57:119-24.
  148. Altered fractionation: limited by mucosal reactions? Radiother Oncol 1998;50:247-60.
  149. R. Randomized clinical trial on accelerated 7 days per week fractionation in radiotherapy for head and neck cancer. Preliminary report on acute toxicity. Radiother Oncol 1996;40:137-45.
  150. Intensity modulated radiation therapy: a clinical review. Br J Radiol 2000;73:459-69.
  151. Conformal radiotherapy and intensity-modulated radiotherapy. Acta Oncologica 2000;39:555-67.
  152. Dysphagia following chemoradiation for locally advanced head and neck cancer. Annals Oncol 2004;15:383-8.
  153. Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy – results of a m ulticentric randomized German trial in advanced head-and-necek cancer. Int J Rad Oncol Biol Phys 2001;50:1161-71.
  154. Prognostic and predictive factors in oral squamous cell cancer: important tools for planning individual therapy? Oral Oncol 2004;40(2):110-9. Review.
  155. Accumulative increase in loss of heterozygosity from leukoplakia to foci of early cancerization in leukoplakia of the oral cavity. Cancer 2001;92:2349-56.
  156. Deciphering gene expression profiled generated from DNA microarrays and their applications in oral medicine. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;97:584-91.
  157. The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck. J Oral Pathol Med 2000;29:413-25.
  158. The prognostic significance of alleleic imbalance at key chromosomal loci in oral cancer. Br J Cancer 1999;79:1821-7.
  159. A case-controlled study confirms that microsatellite assay can identify patients at risk of developing oral squamaous cell carcinoma within a field of cancerization. Cancer Res 2000;60:3893-8.
  160. Impact of genomic instability in risk assessment and chemoprevention of oral premalignancies. Int J Cancer 2002;101:205-9.
  161. Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia. Clin Cancer Res 2000;6:357-62.
  162. The influence of resection and aneuploidy on mortality in oral leukoplakia. N Engl J Med 2004;350:1405-13.
  163. Which putatively pre-malignant oral lesions become oral cancers? J Oral Pathol Med 2003;32:63-70.
  164. Loss of heterozygosity: a potential tool in management of oral premalignant lesions? J Oral Pathol Med 2001;30:513-20.
  165. Two sides of a prevention ‘coin’: adequate screening and better tools. J Oral Pathol Med 2002;31:249-51.
  166. The head and neck radiation oncology patient. Quintessence Int 2003;34(9):693-717.
  167. The medical oncology patient. Quintessence Int. 2005 May;36(5):383-402.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.