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VOLUME 8 , ISSUE 5 ( July, 2007 ) > List of Articles

RESEARCH ARTICLE

An Anticalculus Dentifrice with Sodium Hexametaphosphate and Stannous Fluoride: A Six-month Study of Efficacy

J. Leslie Winston, Thomas Schiff, Susan K. Fiedler, Robert A. Baker

Citation Information : Winston JL, Schiff T, Fiedler SK, Baker RA. An Anticalculus Dentifrice with Sodium Hexametaphosphate and Stannous Fluoride: A Six-month Study of Efficacy. J Contemp Dent Pract 2007; 8 (5):1-8.

DOI: 10.5005/jcdp-8-5-1

License: CC BY-NC 3.0

Published Online: 01-07-2007

Copyright Statement:  Copyright © 2007; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

To compare the anticalculus efficacy of an experimental dentifrice (0.454% stabilized stannous fluoride/ sodium hexametaphosphate) with a negative control.

Methods and Materials

This was a randomized, examiner-blind, parallel group study. After a three-month run-in, qualifying subjects were randomized to the experimental or control dentifrice to use twice a day for six months. Volpe-Manhold Index (V-MI) and oral soft tissue examinations were conducted at baseline, three, and six months. Additional analyses were performed separately at three and six months on three subgroups categorized into high, medium, and low calculus-forming subjects.

Results

Compared to the control group, the experimental dentifrice group had a mean calculus score statistically significantly lower at both three months (50%) and six months (55%) post-treatment (p<0.001). Compared to control scores, mean experimental dentifrice calculus scores at three and six months were statistically significantly lower at both points in time for high, medium, and low calculus forming sub-groups (p<0.001). Both products were generally well tolerated.

Conclusion

The experimental dentifrice revealed significant anticalculus efficacy compared to the control regardless of levels of baseline calculus formation.

Clinical Significance

The stannous fluoride/sodium hexametaphosphate dentifrice technology is an effective calculus inhibitor for home care.

Citation

Winston JL, Fiedler SK, Schiff T, Baker RA. An Anticalculus Dentifrice with Sodium Hexametaphosphate and Stannous Fluoride: A Six-month Study of Efficacy. J Contemp Dent Pract 2007 July;(8)5:001-008.


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