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VOLUME 9 , ISSUE 4 ( May, 2008 ) > List of Articles

RESEARCH ARTICLE

Ozone Therapy in Medicine and Dentistry

Carlos Goes Nogales, Patricia Helena Ferrari, Efraim Olszawer Kantorovich, José Luiz Lage-Marques

Citation Information : Nogales CG, Ferrari PH, Kantorovich EO, Lage-Marques JL. Ozone Therapy in Medicine and Dentistry. J Contemp Dent Pract 2008; 9 (4):75-84.

DOI: 10.5005/jcdp-9-4-75

License: CC BY-NC 3.0

Published Online: 01-01-2010

Copyright Statement:  Copyright © 2008; The Author(s).


Abstract

Aim

The purpose of this review is to present the potential for the incorporation of ozone therapy into the practice of dentistry.

Background

Ozone gas has a high oxidation potential and is 1.5 times greater than chloride when used as an antimicrobial agent against bacteria, viruses, fungi, and protozoa. It also has the capacity to stimulate blood circulation and the immune response. Such features justify the current interest in its application in medicine and dentistry and have been indicated for the treatment of 260 different pathologies. It can be used for the treatment of alveolitis as a replacement for antibiotic therapy, as a mouthwash for reducing the oral microflora, as well as the adherence of microorganisms to tooth surfaces. Ozone has been shown to stimulate remineralization of recent caries-affected teeth after a period of about six to eight weeks.

Conclusion

The future of ozone therapy must focus on the establishment of safe and well-defined parameters in accordance with randomized, controlled trials to determine the precise indications and guidelines in order to treat various medical and dental pathologies. Scientific support, as suggested by demonstrated studies, for ozone therapy presents a potential for an atraumatic, biologically-based treatment for conditions encountered in dental practice.

Citation

Nogales CG, Ferrari PA, Kantorovich EO, Lage-Marques JL. Ozone Therapy in Medicine and Dentistry. J Contemp Dent Pract 2008 May; (9)4:075-084.


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  1. The use of ozone in medicine. 4th ed, 2002.
  2. Oxygen-ozone therapy: a critical evaluation, 2002.
  3. [Ozonetherapy: Medical and Dentistry application] [Dissertation]. São Paulo (Brazil): University of São Paulo; 2006.
  4. Ozone as Janus: this controversial gas can either toxic or medically useful. Mediators Inflamm. 2004; 13(1):3-11.
  5. Assessment of the safety of two ozone delivery devices. Journal of Dentistry 2007; 37:195-200.
  6. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic dentures plates. Oral Microbiology and Immunology 2005; 20:206-10.
  7. The use of ozone in dentistry and maxillofacial surgery: A review. Quintessence International 2006; 37(5):353-359.
  8. Aplicación de la ozonoterapia en el tratamiento de la alveolitis. Revista Cubana de Estomatologia 1997; 34(1):21-4.
  9. Systematic review of the effectiveness and cost-effectiveness of HealOzone for the treatment of occlusal pit/fissure caries and root caries. Health Technology Assessment 2006;10(16):iii-iv, ix-80.
  10. Anti microbial effects of a novel ozone generating device on microorganisms associated with primary root carious lesion in vitro. Caries Res. 2000; 34:498-501.
  11. The use of ozone in dentistry and medicine. Primary Dental Care 2005;12(2):47–52.
  12. The use of ozone in dentistry and medicine. Part 2. Primary Dental Care 2006; 13(1):37-41.
  13. Antibacterial effect of an ozone device and its comparison with two dentin-bonding systems. Eur J Oral Sci. 2006; 114:349-353.
  14. Assessment of the ozone-mediated killing of bacteria in infected dentine associated with non-cavitated occlusal carious lesions. Caries Res. 2007; 41:337-341.
  15. The impact of ozone treatment on enamel physical properties. Am J Dent. 2006; 19(1):67-72.
  16. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiology and Immunology 2004; 19:240-6.
  17. Effect of ozone on oral cells compared with established antimicrobials. European Journal of Oral Sciences 2006; 114:435-440.
  18. Antibacterial activity of ozonized sunflower oil (Oleozon). Journal Applied Microbiology 2001; 90:279-84.
  19. [In vitro evaluation of the antibacterial activity of ozonized water against Staphylococcus aureus] Pesquisa Odontológica Brasileira 2001; 15(1):18-22.
  20. An in vitro evaluation of the ability of ozone to kill a strain of Enterococcus faecalis. Int Endod J. 2005;38:22–9.
  21. [Comparison of the effects of HPG paste (calcium hydroxide, camphorated paramonochlorophenol and glycerine) or ozonized oil used as intracanal medicaments in the treatment of pulpless teeth associated with periradicular lesions: a radiographic, histopathological and histobacteriological study in dogs.] [PhD thesis] Rio de Janeiro, Brazil: Faculdade de Odontologia da Universidade Federal do Rio de Janeiro; 2002.
  22. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endod. 2004; 30(11):778-81.
  23. (PhD thesis). São José dos Campos: Faculdade de Odontologia de São José dos Campos, Brazil: Universidade Estadual Paulista; 2006.
  24. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. Int Endod J. 2007; 40:85-93.
  25. [The use of ozone in Dentistry]. 16° Campinas International Conclave 2005; 115.
  26. Ozone therapy for the treatment of dental caries. Cochrane Database Systemic Review 2004;3:CD004153.
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