The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 9 , ISSUE 6 ( September, 2008 ) > List of Articles

RESEARCH ARTICLE

Short-term Effects of a Combination Product Night-time Therapeutic Regimen on Breath Malodor

Robert W. Gerlach, Matthew L. Barker, Svetlana Farrell, Amy Walanski

Citation Information : Gerlach RW, Barker ML, Farrell S, Walanski A. Short-term Effects of a Combination Product Night-time Therapeutic Regimen on Breath Malodor. J Contemp Dent Pract 2008; 9 (6):1-8.

DOI: 10.5005/jcdp-9-6-1

License: CC BY-NC 3.0

Published Online: 01-09-2008

Copyright Statement:  Copyright © 2008; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

To evaluate the malodor reduction benefits of a therapeutic night-time oral hygiene regimen that combined antibacterial toothpaste and mouthrinse with an oscillating-rotating rechargeable power toothbrush.

Methods and Materials

An independent clinical trial was conducted using a randomized, negative-controlled, single blind, two treatment, 4-period crossover design. After completing a 1-week acclimation period, subjects were randomly assigned to a treatment sequence consisting of the following two regimens: (1) a night-time regimen of Crest® Pro-Health® Night dentifrice, Crest® Pro-Health® Night rinse, and Oral-B® Vitality™ Precision Clean™ power toothbrush and (2) a control regimen of Crest® Cavity Protection dentifrice and an ADA manual toothbrush. Each treatment period started with an overnight baseline volatile sulfur compounds (VSCs) Halimeter® measurement, followed by twice daily use of the assigned regimen. Post-treatment overnight malodor was assessed at 24 hours. There were 2-day washout periods between treatments. All procedures were repeated with the next assigned regimen, through four crossover periods.

Results

Twenty-five subjects completed the study. Twice daily use of the therapeutic night-time regimen resulted in a significant (p>0.001) 35% reduction of mean VSC levels in the overnight breath compared to the control regimen.

Conclusion

One-day use of a night-time regimen consisting of a therapeutic paste, rinse, and an oscillatingrotating rechargeable power toothbrush provided a 35% reduction in overnight breath malodor compared to regular brushing.

Clinical Significance

Combining a proven therapeutic dentifrice, mouthrinse, and advanced design toothbrush in a single regimen is an efficient means of maximizing breath odor reductions.

Citation

Farrell S, Barker ML, Walanski A, Gerlach RW. Short-term Effects of a Combination Product Nighttime Therapeutic Regimen on Breath Malodor. J Contemp Dent Pract 2008 September; (9)6:001-008.


PDF Share
  1. The effect of odor and breath odor on social acceptance. J Breath Res. 2008;Feb 7;(2):1-4.
  2. Counseling and treating bad breath patients: A step-by-step approach. J Contemp Dent Pract. 2001;May;(2)2:046-061.
  3. Fundamentals of breath malodor. J Contemp Dent Pract. 2001;Nov;(2)4:001-017.
  4. Halitosis update: A review of causes, diagnoses and treatments. J Calif Dent Assoc. 2007;Apr;(35)4:1-8.
  5. Overnight malodor effect with a 0.454% stabilized stannous fluoride sodium hexametaphosphate dentifrice. Compen Contin Educ Dent. 2007;Dec;28(12)658-61; quiz662, 671.
  6. Assessing the contribution of anaerobic microflora of the tongue to oral malodor. J Am Dent Assoc. 1995; 126:1384-1393.
  7. Oral malodor. J Am Dent Assoc. 2003;Feb;134(2):209-14.
  8. Morning breath odor: Influence of treatments on sulfur gases. J Dent Res. 2000; 79:1773-1777.
  9. Self-estimation of oral malodor. J Dent Res. 1995;Sept;74(9):1577-1582.
  10. The science of bad breath. Sci Am. 2002; 286(4):72-79.
  11. A review of the current literature on aetiology and mesaurement methods of halitosis. J Dent. 2007; 35:627-35.
  12. Reproducibility and sensitivity of oral malodor mesurements with a portable sulfide monitor. J Dent Res. 1991; 70:1436-40.
  13. Clinical oral malodor measurement with a portable sulfide monitor. Oral Diseases. 2008; 14:264-9.
  14. H2S generation and Eh reduction in cysteine challenge testing as a means of determining the potential of test products and treatments for inhibiting oral malodor. J Breath Res. 2008;2; doi:10.1088/1752-7155/2/1/017-18.
  15. Relationship between volatile sulfur compounds, BANAhydrolyzing bacteria and gingival health in patients with and without complaints of oral malodor. J Clin Dent. 1994; 4:114-9.
  16. Reduction of oral malodor by oxidyzing losenges. J Periodontol. 1997; 68:1176-81.
  17. Characteristics of patients complaining of halitosis and the usefulness of chromatography for diagnosing halitosis. Oral Surg, Oral Med, Oral Pathol, Oral Radiol. and Endodont. 2001; 91:531-4.
  18. Comparison of volatile sulfur compound concentrations measured with a sulfide detector vs. gas chromatography. J Dent Res. 2002; 81:140-3.
  19. Review of the Antimicrobial Action of Stannous Fluoride. J Clin Dent. 1990; 2(1):22-27.
  20. retention of stannous ion in dental plaque: Pharmacokinetic modeling. J Dent Res. 2007;86(Spec Iss). Abstract 1874.
  21. Sustained Antibacterial Actions of a new Stabilized stannous fluoride dentifrice containing sodium hexametaphosphate. Compend Contin Educ Dent. 2005; 26(9):19-28.
  22. The affinity of chlorhexidine for hydroxyapatite and salivary mucins. J Perio Res. 1970; 5:90-5.
  23. Comparison of in vitro and in vivo antibacterial properties of anticeptic mouthrinses containing chlorhexidine, alexidine, CPC and hexetidine. Relevance to mode of action. J Clin Periodontol. 1981; 8:295-310.
  24. Clinical association of volatile sulfur compounds, Halimeter values, organoleptic score and tongue coating in oral malodor. Oral Dis. 2005;Mar;11(Supplement 1):99-99(1).
  25. , Wilson A, Zhang, W. Correlation and Consistency in Evaluating Oral Odor. J Dent Res. 2004;82(Spec Iss A) Abstract 327.
  26. Subjective patients’ opinion and evaluation of halitosis using Halimeter and organoleptic scores. Oral Dis. 2005; (11)Suppl 1[Abstract]:86-8.
  27. Halitosis measurement by an industrial sulfide monitor. J Periodontol 1991;62:487–9.
  28. Oral malodor reduction by a combination of chemotherapeutical and mechanical treatments. Clin Oral Investig. 2006;Jun;10(2):157-63.
  29. Breath effects of three marketed dentifrices: a comparative study evaluating single and cumulative use. J Clin Dent. 1998; 9(4):83-8.
  30. Winston JL. Comparison of short-term breath efficacy of stannous fluoride and triclosan/copolymer dentifrice. J Dent Res. 2007;86(Spec Iss). Abstract 2042.
  31. , Fiedler SK, He T, Baker RA, Winston JL. Short-term breath efficacy of stannous fluoride dentifrice. J Dent Res. 2007;86(Spec Iss). Abstract 2038.
  32. Long-term breath efficacy of stannous fluoride dentifrice. J Dent Res. 2007;86(Spec Iss). Abstract 0125.
  33. Breath protection efficacy of a commercial CPC mouthrinse. J Dent Res. 2006;85: Abstract 2051.
  34. Comparison of two power toothbrushes versus manual toothbrushing. J Dent Res. 2006;85:Abstract 2043.
  35. Manual versus powered toothbrushing for oral health. Cochrane Database Syst Rev. 2005;Apr 18;(2):CD002281. Review.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.