The Journal of Contemporary Dental Practice

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 16 , ISSUE 5 ( May, 2015 ) > List of Articles


Unveiling the Molecular Signature of Salivary Gland Neoplasms with Tumor-specific Fusion Oncogenes

Roopa Rao, Thirumal Raj

Citation Information : Rao R, Raj T. Unveiling the Molecular Signature of Salivary Gland Neoplasms with Tumor-specific Fusion Oncogenes. J Contemp Dent Pract 2015; 16 (5).

DOI: 10.5005/jcdp-16-5-i

License: CC BY-NC 3.0

Published Online: 01-01-2011

Copyright Statement:  Copyright © 2015; The Author(s).


PDF Share
  1. Fusion oncogenes and tumor type specificity—insights from salivary gland tumors. Seminars in Cancer Biology, 2005:224-235
  2. Fusion Oncogenes in Salivary Gland Tumors: Molecular and Clinical Consequence. Head and Neck Pathol, 2013; 7:S12-S19
  3. Pitman, Diana Bell, Feriyl Bhaijee, Pepper DJ, Pitman KT, Bell D. New developments in the molecular pathogenesis of head and neck tumors: a review of tumor-specific fusion oncogenes in mucoepidermoid carcinoma, adenoid cystic carcinoma, and NUT midline carcinoma. Annals of Diagnostic Pathology, 2011:69-77
  4. Fusion oncogenes in tumor development. Seminars in Cancer Biology, 2005:236-243
  5. Non-random chromosome rearrangements in adenoid cystic carcinoma of the salivary glands. Genes Chromosomes Cancer, 1994(10):115-121.
  6. Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc Natl Acad Sci USA. 2009;106:187:40-44.
  7. Analysis of MYB Expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms. Mod Pathol. 2011;24:11:69-76.
  8. MYB expression and translocation in adenoid cystic carcinoma and other salivary gland tumors with clinicopathological correlation. Am J Surg Pathol. 2011;35:92-99.
  9. Recurrent rearrangements of 11q14-22 in mucoepidermoid carcinoma. Cancer Genet Cytogenet. 1994;74:77-83.
  10. t(11;19) (q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signalling pathway. Nat Genet. 2003;33:208-213.
  11. Genomic profiles and CRTC1-MAML2 fusion distinguish different subtypes of mucoepidermoid carcinoma. Mod Pathol. Sep 2012;28:154. doi:10.1038/modpathol.
  12. Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors. Exp Cell Res. 2004;292:21-28.
  13. The MECT1-MAML2 gene fusion and benign Warthin0s tumour: is the MECT1- MAML2 gene fusion specific to mucoepidermoid carcinoma? J Mol Diagn. 20068394-5.42.
  14. A closer look at warthin tumors and the t(11;19). Cancer Genet Cytogenet. 2008; 180:135-139.
  15. POU5F1, encoding a key regulator of stem cell pluripotency, is fused to EWSR1 in hidradenoma of the skin and mucoepidermoid carcinoma of the salivary glands. J Pathol. 2008;215:78-86.
  16. EWSR1-ATF1 fusion is a novel and consistent finding in hyalinizing cler-cell sarcoma of salivary gland. Genes Chromosomes Cancer. 2011;50:559-570.
  17. Mammary analogue secretory carcinoma of the salivary glands with ETV6-NTRK3 gene fusion. Am J Surg Pathol. 2011;35:1600-1602.
  18. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell. 2002;2:367-376.
  19. Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Nat Genet. 1997;15:170-174.
  20. Identification of NFIB as recurrent translocation partner gene of HMGIC in pleomorphic adenomas. Oncogene. 1998;16:865-872.
  21. Highresolution genomic profiling of adenomas and carcinomas of the salivary glands reveals amplification, rearrangement, and fusion of HMGA2. Genes Chromosomes Cancer. 2009;48:69-82
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.