[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:2] [Pages No:507 - 508]
DOI: 10.5005/jp-journals-10024-3550 | Open Access | How to cite |
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:509 - 514]
Keywords: Cocktail impression, Conventional impression, Modified functional impression, Wire impression technique
DOI: 10.5005/jp-journals-10024-3544 | Open Access | How to cite |
Abstract
Aim: This study aimed to evaluate the effect of different definitive impression techniques for the resorbed mandibular ridge on the retention of lower complete dentures. Materials and methods: Ten completely edentulous male patients with severe atrophic mandibular ridge were selected from the Prosthodontic Department's outpatient clinic, Faculty of Dentistry, Sinai University (Kantara branch). Each patient received four dentures. Dentures were divided into four groups according to the type of final impression, Group I: Conventional impression techniques (open mouth technique), Group II: Cocktail impression techniques, Group III: Modified functional impression technique, and Group IV: Wire impression technique. Each denture was used for one month and at the end of the month the retention test was carried out and the results were tabulated and statistically analyzed. Results: There is a statistically significant difference between the groups. The results also showed that the highest mean value was in group IV, whereas the lowest mean value of retention was in group I. Conclusion: Wire impressions produce lower dentures with higher retention, whereas conventional impressions produce lower dentures with the lowest retention, so it is considered to be more advantageous. Clinical significance: The wire impression technique is superior in the management of resorbed ridges as compared with other techniques.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:515 - 520]
Keywords: Antiseptic-impregnated sutures, Bacterial adherence, Triclosan-coated sutures, Wound healing
DOI: 10.5005/jp-journals-10024-3553 | Open Access | How to cite |
Abstract
Aim: To assess the efficacy of antiseptic-coated silk sutures with triclosan-coated polyglactin 910 suture in reducing bacterial colonization after oral surgical procedures. Materials and methods: The patients who required multiple sutures after surgical procedures in the mandible were the study subjects. The sites of suturing were divided into three groups. Group A – surgical site receiving black-braided silk suture (control group). Group B – surgical site receiving triclosan-coated Polyglactin 910 suture (experimental group). Group C – surgical site receiving antiseptic-coated silk suture (experimental group). Evaluation was done on the 3rd postoperative and 7th postoperative day. Microbial adherence was evaluated by microbiological study. Results: The mean comparison of microbial count between 3rd and 7th post-op day in the three groups shows an increased microbial colonization in the control group when compared with the experimental groups. The combined mean microbial adherence in the three groups showed microbial count in the uncoated silk suture (group A) as 10.35 ± 3.74, triclosan-coated suture (group B ) as 6.28 ± 2.17 and iodoform + calendula oil-coated suture (group C) as 7.1 ± 2.02 which is statistically significant (p < 0.05). Conclusion: The present research concluded that the pomade-coated silk suture is as efficient as triclosan-coated VICRYL PLUS Polyglactin 910 sutures in reducing the bacterial colonization in intraoral wound healing. Clinical significance: The pomade (iodoform + calendula oil) may be advocated in the field of oral and maxillofacial surgery for impregnating the suture materials which act as an antiseptic agent and a promoter of wound healing which is easily accessible and also cost-effective.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:24] [Pages No:521 - 544]
Keywords: Alloy adhesive primers, Alloy–resin interface, Base alloys, Bond strength, Noble alloys
DOI: 10.5005/jp-journals-10024-3514 | Open Access | How to cite |
Abstract
Aim: The present systematic review aimed to report the studies concerning the primers in improving bond strength and identifying pertinent primers for a particular dental alloy by adhering to PRISMA precepts. Materials and methods: PubMed and Semantic Scholar databases were scoured for articles using 10 search terms. In vitro studies satisfying the inclusion criteria were probed which were meticulously screened and scrutinized for eligibility adhering to the 11 exclusion criteria. The quality assessment tool for in vitro studies (QUIN Tool) containing 12 criteria was employed to assess the risk of bias (RoB). Results: A total of 48 studies assessing shear bond strength (SBS) and 15 studies evaluating tensile bond strength (TBS) were included in the qualitative synthesis. Concerning SBS, 33.4% moderate and 66.6% high RoB was observed. Concerning TBS, 26.8% moderate and 73.2% high RoB was discerned. Seventeen and two studies assessing SBS and TBS, respectively, were included in meta-analyses. Conclusions: Shear bond strength and TBS increased for the primed alloys. Cyclic disulfide primer is best-suited for noble alloys when compared with thiol/thione primers. Phosphoric acid- and phosphonic acid ester-based primers are opportune for base alloys. Clinical significance: The alloy–resin interface (ARI) would fail if an inappropriate primer was selected. Therefore, the selection of an appropriate alloy adhesive primer for an alloy plays a crucial role in prosthetic success. This systematic review would help in the identification and selection of a congruous primer for a selected alloy.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:545 - 550]
Keywords: Delta E, Easyshade, Resin cement, Spectrophotometer, Zirconia
DOI: 10.5005/jp-journals-10024-3554 | Open Access | How to cite |
Abstract
Aim: The color difference between the final shade of restorations milled from different zirconia blocks, and the control teeth in the esthetic zone is yet uncertain. Materials and methods: For eight patients who required a singular maxillary central incisor restoration, twenty-four crowns made of zirconia were created. These were grouped into three categories based on the shade and nature of zirconia (Zr) utilized (white core, colored core, and monolithic high-translucency (ht) Zr crowns). The difference in color (ΔE) between the three zirconia crowns and the neighboring teeth was calculated by the use of Easyshade spectrophotometer. Two shades of resin luting cement were used. The measured ΔE values were evaluated based on a clinically acceptable color difference of 1.6ΔE, which is not visible to the human eye. Results: Among the three groups, no differences of statistical significance were observed in terms of ΔE with different Zr types and resin cement color. Conclusion: Within the limits of this study, the usage of different shades of zirconia blanks and resin cements did not display a statistically significant effect on the final color of the crown. Clinical significance: Changing the shade of resin cements does not appear to add value to the final shade of crown. In addition, the generation of zirconia does not influence the shade of the crown. Crowns made of zirconia can be cemented with opaque or transparent cement with no effect on the final color.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:5] [Pages No:551 - 555]
Keywords: Antibacterial efficacy, Matricaria recutita, Porphyromonas gingivalis, Prevotella intermedia.
DOI: 10.5005/jp-journals-10024-3543 | Open Access | How to cite |
Abstract
Aim: To evaluate in vitro the antibacterial efficacy of Matricaria recutita (chamomile) essential oil at 50 and 75% against Porphyromonas gingivalis ATCC 33277 and Prevotella intermedia ATCC 25611 at 24 and 48 hours. Material and methods: The sample consisted of 80 discs and Mueller–Hinton Agar, the medium chosen for the culture. To determine the bacterial sensitivity, discs were placed in each Petri dish with concentrations of essential oil at 50 and 75%, distilled water and 0.12% chlorhexidine. Subsequently, the inhibition halos were measured in millimeters at 24 and 48 hours after culture, with the Kirby–Bauer disk diffusion method. Results: In groups treated with Porphyromonas gingivalis, measurements at 24 and 48 hours yielded 22.14 ± 2.61 and 22.63 ± 2.67 mm for 0.12% chlorhexidine, 18.90 ± 0.41 and 19.22 ± 0.54 mm for 75% essential oil, and 15.55 ± 0.45 and 15.77 ± 0.46 mm for 50% essential oil, respectively. No statistically significant differences were observed among the groups (p > 0.05). Conclusion: No significant differences were found between the antibacterial efficacy of 0.12% chlorhexidine and 50 and 75% essential oil of Matricaria recutita on Porphyromonas gingivalis and Prevotella intermedia at 24 and 48 hours. Clinical significance: The study demonstrates that essential oil derived from Matricaria recutita may effectively combat bacteria associated with periodontal disease. This discovery has the potential to impact dental practice by introducing a natural treatment option. Further research is warranted to fully elucidate the clinical significance and potential applications of this finding.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:4] [Pages No:556 - 559]
Keywords: Denture cleansers, Flexural strength, Heat-polymerizing resin, Surface roughness
DOI: 10.5005/jp-journals-10024-3508 | Open Access | How to cite |
Abstract
Aim: The purpose of the current study was to evaluate the impact of three different denture cleansers on the strength and surface roughness of heat-polymerizing resin. Materials and methods: A total of 120 resin discs (10 mm in diameter and 2 mm thick) were created using a stainless steel mold for surface roughness testing and flexural strength testing (in accordance with the American Dental Association (ADA) Specification No.12). Samples were divided into one of three groups (40 samples in each group): group I: Clanden, group II: Clinsodent, group III: Fittydent. Samples were immersed in denture-cleansing solutions for 30 minutes every day, and this process was repeated over a period of 15 days. Samples were stored in distilled water at room temperature in between the immersions. A surface analyzer was utilized to compare the surface roughness of each sample before and after immersion treatments. For recording flexural strength, each sample was subjected to three-point bending test by mounting samples on Universal testing machine. Comparing mean values between groups using one-way ANOVA and the Tukeys honest significant difference (HSD) post hoc test. A significance level of 0.05 was used for all statistical calculations Results: After 15 days, the maximum change of mean surface roughness of heat-polymerizing resin was found in Clanden denture cleanser group (2.64 ± 0.12) followed by Clinsodent group (2.26 ± 0.09) and Fittydent group (1.92 ± 0.06). After 15 days, the maximum change of mean flexural strength changes of heat-polymerizing resin was found in Clanden denture cleanser group (94.78 ± 0.14), followed by Fittydent group (98.64 ± 0.03) and Clinsodent group (99.26 ± 0.21). Conclusion: Within the limitation, the current study concluded that changes were observed in surface roughness and flexural strength of all heat-polymerizing resin samples after immersion in all three denture cleansers; but least surface roughness and flexural strength changes were observed with the Fittydent cleanser group and Clinsodent group, respectively. Clinical significance: Cleaning dentures is crucial for maintaining both the prosthesis and oral health; therefore, it is necessary to select a cleanser that is effective without negatively affecting the base resin's qualities over time.
Tooth Shade and Blood Type: A Descriptive Cross-sectional Study in Tunisia
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:560 - 565]
Keywords: Age, Blood type, Color, Correlation, Cross-sectional study, Gender, Investigation, Tooth shade
DOI: 10.5005/jp-journals-10024-3538 | Open Access | How to cite |
Abstract
Aim: The aim of the study was to assess the prevalence of tooth shade and its correlation with blood type. Materials and methods: This study analyzed 312 blood donors at the university Hospital in Monastir between November 2021 and June 2022. Both male and female subjects were included, with ages ranging from 18 to 60 years old. Patients with certain dental conditions or habits were excluded from the study. The study recorded various information about blood donors, including gender, age, governorate of origin, tooth shade, and blood type. The tooth shade values were recorded using A–D shade guide. Data input and tabulation were carried out using Microsoft Excel 2016 and SPSS (version 25.0). Results: The study included 312 participants, with 85.58% males and 14.42% females. Tooth shade value B was the most prevalent (43%), and D was the least prevalent (7%). The statistical analysis showed that there was no significant link between tooth shade and blood type. However, there were three statistically significant categories: Blood type B/Tooth shade B, Blood type O/Tooth shade C, and Blood Type O/Tooth shade D. Conclusion: The study examined the link between tooth color and blood type but did not find a significant link. However, significant values were found in different subgroups. A wider selection of subjects and a more rigorous measurement equipment might lead to more favorable results. Clinical significance: By considering the patient's blood type alongside other relevant factors, clinicians can enhance the accuracy and precision of tooth shade selection, resulting in harmonious and natural-looking dental restorations. This approach improves patient satisfaction and acceptance.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:4] [Pages No:566 - 569]
Keywords: Abutments, Dental implants, Microbial leakage, Microgap
DOI: 10.5005/jp-journals-10024-3509 | Open Access | How to cite |
Abstract
Aim: The purpose of the current study was to evaluate Titanium and Bioneck TRI implant-abutment interfaces for microgaps and microbiological leakage. Materials and methods: In this in vitro experiment, 40 dental implants were split into two groups, each of which had 20 samples. Group I: Titanium dental implant, group II: Bioneck TRI. E. coli strain was cultivated in MacConkey media for 24 hours at 37°C. To achieve a bacterial concentration of 1 x 108 colony-forming units per mL at 0.5 scale of MacFarland, the brain-heart infusion (BHI) broth was injected. The CFU count was done to evaluate the microbial leakage. The parts were first submerged, carefully cleaned in an ultrasonic bath, and then installed using a digital torque meter with a 20 N/cm preload. These were attached to a stub of approximately 13 mm using carbon tape, and the microgap evaluation was performed using a scanning electron microscope at a magnification of x1000. Unpaired t-test was used for the calculated data's statistical analysis. The p-value less than 0.05 was considered as statistically significant. Results: The maximum microbial leakage was in Bioneck TRI implants (10000 ± 0.01) followed by Titanium dental implants (8.60 ± 3.16). The mean difference was 9991.40 and there was a statistically significant difference found between the two different groups. The maximum microgap was found in the Bioneck TRI implants (9.72 ± 0.96), followed by Titanium dental implant (6.82 ± 1.10) and there was a statistically significant difference was found between the groups (p < 0.001). Conclusion: The present study concluded that the microorganisms can infiltrate the microgap between the implant and abutment interface. When compared with Titanium dental implants, Bioneck TRI implants showed significantly higher levels of microbial leakage. Clinical significance: A microgap between the implant and abutment connection might operate as a bacterial source, may produce inflammation, even osseointegration in danger, and subsequently alter clinical and histological parameters. Therefore, having an understanding of the compatible components aids in overcoming treatment planning challenges.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:570 - 575]
Keywords: Bibliometric analysis, Dental protheses, Social impact, Sexual performance
DOI: 10.5005/jp-journals-10024-3545 | Open Access | How to cite |
Abstract
Aim: To explore and conduct a bibliometric mapping of scientific production on quality of life, social impact, and security in love relationships in patients with dental prostheses. Materials and methods: This study is a bibliometric, retrospective, observational analysis of scientific publications indexed in Scopus from 2017 to 2022. The search was conducted on March 8, 2023, using the MESH thesaurus and a defined search strategy. Fifty-two relevant studies were identified and exported to the SciVal program for further analysis. Various bibliometric indicators were used to analyze scientific production, including number of citations, publication, authorship, institution and collaboration, journal quartile, country of origin, h-index, CiteScore 2020, SCImago Journal Rank (SJR), Field Weighted Citation Impact (FWCI), and Source Normalized Impact per Paper (SNIP). Results: Most of the articles (39) were in the highest quality quartiles (Q1 and Q2). Brazil produced a total of 15 scientific publications with a domain-weighted impact of 0.65, while Germany produced a total of 11 publications with a domain-weighted impact of 3.15. The results show that international collaboration (32.7%) and national collaboration (38.5%) are more frequent. The most influential author is Daniel Ralph Reißmann with a total of 72 publications followed by Oliver Schierz with 27 publications. German institutions (University of Hamburg, Leipzig University, and Ludwig Maximilian University of Munich) lead in scientific productivity. The Journal of Prosthetic Dentistry (Q1) has the highest number of articles (7) and a citation-to-publication ratio of 14.7. Conclusion: Scientific production on quality of life in patients with dental prostheses is still scarce, although its dissemination is mainly in high-impact scientific journals. Clinical significance: This study provided a deeper understanding of how dental prostheses affect people's lives. This can provide practitioners with valuable information to make clinical treatment decisions to improve quality of life. In addition, it can guide future studies to deepen the understanding of this topic in the clinical setting.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:6] [Pages No:576 - 581]
Keywords: Bilayered, Ceramic, Fracture resistance, Monolith, Zirconia
DOI: 10.5005/jp-journals-10024-3546 | Open Access | How to cite |
Abstract
Aim: To compare the fracture resistance and the mode of failure between monolith second-generation zirconia and bilayered first-generation zirconia single crowns cemented by resin cement and glass ionomer cement (GIC). Materials and methods: A total of 36 maxillary first premolar crowns (5 mm in length × 4 mm in cervical diameter, with a base of 6 mm) were computer-aided design–computer-aided manufacturing (CAD–CAM) milled. They were divided into the following two groups (n = 18) according to the fabrication techniques: Group M – monolith zirconia crown (1-mm axial thickness and 2-mm occlusal thickness) and group B – bilayer zirconia crown (0.5-mm axial thickness and 1-mm occlusal thickness). Each group was further subdivided into the following two subgroups (n = 9) according to the cement used: Subgroup G – cemented using GIC; subgroup R – cemented using resin cement. All crowns were cemented to their corresponding resin dies and stored in distilled water for 72 hours. Each specimen was mounted to the lower member of the universal testing machine with a load cell of 5 kN and a crosshead speed of 0.5 mm/minute. Failure modes were analyzed for fractured parts using scanning electron microscopy (SEM). Results: Subgroup MR recorded the highest fracture resistance mean value (3616 ± 347.2 N) while the BG subgroup recorded the statistically significant lowest fracture resistance mean value (1728.7 ± 115.3 N). One-way analysis of variance (ANOVA) followed by pairwise Tukey's post hoc tests revealed a statistically significant difference (p = 0.0001) between groups M and B. One-way ANOVA followed by pairwise Tukey's post hoc tests also showed a statistically significant difference (p = 0.0297) between the types of cement used (subgroups G and R). Conclusion: Monolith zirconia crowns had better mean fracture resistance than bilayered zirconia crowns. Resin cement improved the fracture resistance compared to GIC. Monolith zirconia crowns showed bulk fracture while bilayered zirconia crowns showed chipping fracture. Clinical significance: Monolith zirconia crowns present a good prosthetic alternative overcoming the veneer chipping drawback of bilayered zirconia crowns. In addition, resin cement could increase the fracture resistance of zirconia crowns.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:5] [Pages No:582 - 586]
Keywords: Dental arch, Donders space, Intercanine width, Intermolar width, Myofunctional appliance
DOI: 10.5005/jp-journals-10024-3547 | Open Access | How to cite |
Abstract
Aim: To evaluate the changes in the intraoral dynamic space with myofunctional therapy in skeletal class II division 1 malocclusion using three-dimensional digital volume tomography (3D-DVT). Materials and methods: The study type is observational and the duration of intervention was 3 years. Dental casts obtained from 20 samples of 11–14 years age-group were collected and 3D-DVT scans were performed prior to and after the myofunctional therapy. The parameters depicting the arch perimeter, arch width, arch length, arch shape, and arch volume on dental cast were used in the study using several linear and volumetric measurements. All parameters were compared before and after myofunctional therapy using t-test. Results: The Intraoral volume before myofunctional therapy (T0) was 5.59 mL and after myofunctional therapy (T1), it was 7.22 mL. Significant changes were seen in intraoral volume, arch perimeter, arch length, and intercanine and intermolar arch width and the arch shape. Linear and volumetric measurements were increased after myofunctional therapy. Conclusion: Myofunctional appliances lead to an expansion in the anteroposterior and sagittal direction thus increasing the Donders space and leading to proper formation of dental arches and proper positioning of the teeth. Clinical significance: Myofunctional therapy is an effective method of increasing arch width, length, and volume. This therapy can be used in routine practices in young children with constricted arch and improvement in facial esthetic.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:8] [Pages No:587 - 594]
Keywords: Food simulating liquids, Multiple-step polishing system, Surface gloss, Surface roughness and two-step polishing system
DOI: 10.5005/jp-journals-10024-3548 | Open Access | How to cite |
Abstract
Aim: The purpose of this research was to explore how various finishing and polishing techniques affect the surface roughness (Ra) and gloss of flowable bulk-fill injectable resin composite utilized for posterior teeth restoration, following exposure to a range of food-simulating liquids (FSLs) over three months. Materials and methods: This study comprised fifty-six disk specimens of G-aenial™ Bulk Injectable flowable resin composite which were created using a Teflon mold (10 × 4 mm). Two techniques of finishing and polishing (F/P) were employed: The two-step 3M™ Sof-Lex™ F/P spiral wheels system and the multiple-step 3M™ Sof-Lex™ XT finishing disks supplemented by the Ultradent Jiffy HiShine polisher cup system. The Ra and gloss of the prepared specimens were measured using an interference microscope system and Horiba gloss checker respectively, immediately post-finishing and polishing and then reassessed after three months in artificial saliva and Coca-Cola. Results: The two-step system showed a statistically significant difference, exhibiting greater “surface roughness (Ra)” and lower “surface gloss (GU)” mean values compared to the multiple-step system under different storage conditions, particularly after 3 months of storage (p = 0.001). Conclusion: The multiple-step polishing system improved the “Ra” and “GU” of resin composite, suggesting their suitability for posterior resin composite restorations. Acidic media had a deleterious impact on the “Ra” and “GU” of resin composite restoration. Clinical significance: The quality of resin composite restorations can be significantly improved with the correct use of finishing and polishing systems, particularly in complex areas of posterior teeth restorations, leading to successful dental procedures.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:10] [Pages No:595 - 604]
Keywords: Artificial teeth, Bizygomatic width, Dental arch dimensions, Dental prostheses, Facial measurements, Inter-alar width, Inner-canthal width, Mouth width, Yemeni adult
DOI: 10.5005/jp-journals-10024-3511 | Open Access | How to cite |
Abstract
Aim: To investigate the dental arch dimension (width, length, and height) and facial measurements including inner-canthal width (ICW), bizygomatic width (BZW), inter-alar width (IAW), and mouth width (MW), and to assess the correlation between these facial measurements and dental arch width (canine width [CW], inter-first premolar width [I1PW], and inter-first molar width [I1MW]), to establish a preliminary reference for artificial teeth selection in Yemeni adult. Materials and methods: The study included 80 individuals (40 males and 40 females) with symmetrical faces and normal class I occlusion ranging in age from 20 to 35. Maxillary and mandibular stone casts were made for each individual. The dimensions of dental casts and facial measurements, including ICW, BZW, IAW, and MW, were assessed using a digital caliper. The collected data were analyzed by using the SPSS software program. The descriptive statistics for each measurement were made. Differences between males and females were tested using an independent-sample t-test with p-values below 0.05 considered significant. Pearson correlation coefficient between facial measurements and dental arch width was also done. Results: Most dental arch dimensions and facial measurements exhibited larger mean values in the male than in the female group, with the greatest significant difference in the maxillary dental arch width and the lowest in mandibular dental arch length. A highly significant correlation is observed between ICW and maxillary canine width (CW) (r = 0.318, p = 0.004). In contrast, no significant correlation between dental arch width and BZW, IAW, and MW is shown. Conclusions: Within this study's limitations, the ICW can determine the ideal dimension of the artificial teeth in the anterior maxillary arch. While the other facial parameters, including BZW, IAW, and MW, cannot be used for artificial teeth selection in Yemeni populations. Clinical significance: The findings of this study established a reference database of facial measurements and their correlation to dental arch and teeth width in Yemeni populations. So, it can be implemented in artificial teeth and dental prostheses design and construction.
A Bibliometric Perspective on the Relationship between Periodontal Disease and Gestational Diabetes
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:5] [Pages No:605 - 609]
Keywords: Bibliometric analysis, Bibliometrix, Diabetes gestational, Periodontal diseases
DOI: 10.5005/jp-journals-10024-3541 | Open Access | How to cite |
Abstract
Aim: To analyze the bibliometric indicators of the world scientific production on periodontal disease and gestational diabetes. Materials and methods: Bibliometric study in which a search strategy was designed with logical operators and MESH terms. After the search and application of selection criteria, 83 articles were included. SciVal, VOSviewer, and the Bibliometrix module of R Studio were used to analyze the metadata. Results: From 2012 to 2021, there is evidence of an increase in scientific dissemination on gestational diabetes and periodontal disease, especially in high-impact journals (79.2%). SUNY Buffalo (6), United State University, and Ege University, Turkey (5) are the most productive; however, the one that received more citations than the global average was the University of Birmingham (FWCI: 5.59). In addition, the United States, Brazil, and India were the most influential countries; while, Graziani F, Akcali A, and Buduneli N, were the most representative authors. The Journal of Periodontology and the Journal of Clinical Periodontology published the most articles, with 13 and 6, respectively. Conclusions: The scientific production on periodontal disease and gestational diabetes is higher in recent years, with a better proportion of articles in high-impact journals. In addition, the United States concentrates many publications, and the activity of Chilean institutions stands out. Clinical significance: The clinical significance of this study lies in its capacity to synthesize the currently available published information regarding the correlation between periodontal disease and gestational diabetes. This study enables researchers and clinicians to ascertain the current level of knowledge on this subject.
[Year:2023] [Month:August] [Volume:24] [Number:8] [Pages:10] [Pages No:610 - 619]
Keywords: Cytotoxicity, Human periodontal stem cells, Mineral trioxide aggregate, MTT assay, Root canal sealers, XTT assay
DOI: 10.5005/jp-journals-10024-3551 | Open Access | How to cite |
Abstract
Aim: This review aimed to evaluate the in vitro studies done with regard to the cytotoxicity associated with mineral trioxide aggregate (MTA)-based root canal sealers. Background: Root canal sealers are used during endodontic treatment as fillers to seal the gaps between the canal gutta-percha cone and canal walls. It is necessary to understand the cytotoxicity of these materials on human-derived cells as these materials interact with human cells periapically. Review results: Six in vitro studies were chosen for review. In these selected studies, along with MTA-based root canal sealers, other sealers were tested for cytotoxicity on human periodontal ligament (PDL) stem cells, human PDL fibroblasts, and human osteoblast cells. Regarding cytotoxicity, the studies were diverse, and most were based on 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2H-tetrazolium bromide) (MTT) assay. In general, the studies suggested that root canal sealers cause mild to severe cytotoxic effects and that several factors influence this effect, such as material setting time, concentration, and duration of exposure. Conclusion: All studies in the review indicated that MTA. Fillapex must be used cautiously as it exhibited the highest cytotoxic effect compared to other MTA-based and non-MTA-based sealers. Clinical significance: Endodontic sealers do serve the purpose of bridging the gaps between the gutta-percha cone and the canal wall but knowing its biocompatibility becomes important as the material is extruded beyond the apical foramen where it comes in contact with the surrounding tissues. The effect of sealers on the surrounding tissues affects the healing and prognosis of the treatment.